FEEDER VESSEL PHOTOCOAGULATION OF SUBFOVEAL CHOROIDAL NEOVASCULARIZATION SECONDARY TO AGE-RELATED MACULAR DEGENERATION

Purpose: This study aimed to assess the feasibility of laser photocoag ulation of feeder vessels of subfoveal choroidal neovascularization (C NV) secondary to age-related macular degeneration. Patients and Method s: Of 170 consecutive patients with subfoveal CNV secondary to age-rel ated macular degeneration, feeder vessels were detected in 37 patients by means of indocyanine green videoangiography using a scanning laser ophthalmoscope. Dye laser photocoagulation was applied to extrafoveal feeder vessels, with the fovea spared. Results: Twenty-six (70%) of t hose 37 patients had complete resolution of exudative manifestations. Persistent or worsened manifestations were seen in 11 patients (30%) b ecause of recurrent CNV or persistent CNV, The visual acuity improved or stabilized in 25 patients (68%). Ten patients (27%) had a final vis ual acuity of 20/40 or better and six patients (16%) had a final visua l acuity of 20/50 to 20/100. Significant factors prognostic of the vis ual outcome of 20/100 or better were small CNV (2 disc areas or smalle r, Fisher's exact probability test, P = 0.041), the absence of white, fibrous tissue in neovascular membranes (Fisher's exact probability te st, P = 0.003), and the closest distance of laser burns to the center of the foveal avascular zone (Fisher's exact probability test, P = 0.0 49). Preoperative visual acuity had a significant positive correlation with final visual acuity (Spearman's rank correlation test, P = 0.007 6). Conclusion: Feeder vessel photocoagulation should be considered as a treatment option for subfoveal CNV secondary to age-related macular degeneration, because no other treatment method has a better visual o utcome.