DIGITAL SUBTRACTION INDOCYANINE GREEN ANGIOGRAPHY OF OCCULT CHOROIDALNEOVASCULARIZATION

Objective: This study aimed to use a new technique for ocular imaging, digital subtraction indocyanine green angiography (DS-ICGA), to evalu ate patients with occult choroidal neovascularization (CNV). Design: T he design was a cross-sectional study of patients with occult CNV. Par ticipants: A total of 31 eyes of 31 patients were studied. Interventio n: Digital subtraction of sequentially acquired indocyanine green angi ographic frames was used to image the progression of the dye front. in eyes with occult CNV. A method of pseudocolor imaging of the choroid was developed that allows differentiation and identification of underl ying choroidal arteries and veins. Results: The DS-ICGA of occult CNV showed consistent findings, Occult CNV was imaged with greater detail and in a shorter period of time than with conventional indocyanine gre en angiography. The fundus landmarks were retained with DS-ICGA much b etter than with conventional indocyanine green angiography. Conclusion s: The DS-ICGA uses time to dissect the choroidal circulation. With DS -ICGA, occult CNV could be imaged more quickly and in greater detail t han with conventional imaging techniques. The DS-ICGA may improve the authors ability to image, and subsequently treat, occult CNV.