Rates at which AP-PCR patterns diverge among isolated taxa were examin
ed to test whether they exhibit clocklike regularity. The results show
ed that rates of divergence differed significantly among the groups ex
amined (primates, antelopes, and Hawaiian Drosophila grimshawi). There
fore, AP-PCR divergence rates cannot be used as a ''universal clock''
with an invariant rate in all animals. Nevertheless, within each group
, a strong relationship existed between degree of AP-PCR pattern diver
gence and time since separation of isolated taxa. Thus, AP-PCR diverge
nce may prove useful for dating evolutionary events if calibrated with
in a more limited taxon.