PATIENTS WITH EPILEPSY AND PSYCHOSIS TREATED WITH VIGABATRIN

Eight patients with difficult to control epilepsy and an active or a h istory of psychosis were treated with vigabatrin, and the results of t his clinical intervention are described. In five cases there was no un toward deterioration of the mental state, in three cases a change was reversed by judicious adjustment of both the anticonvulsant and psycho tropic medications. Recommendations for the use of new anticonvulsants in patients with comorbid psychopathology and epilepsy are given. (C) 1998 by Elsevier Science Inc. All rights reserved.