B. Carbonne et al., HIGHER ENDOTHELIN CONCENTRATIONS IN THE FETOPLACENTAL UNIT OF PREGNANT-WOMEN OF AFRICAN ANCESTRY, American journal of obstetrics and gynecology, 178(3), 1998, pp. 491-492
Immunoreactive endothelin was assayed in maternal and fetal biologic f
luids of women of African and European ancestry with normal singleton
pregnancies undergoing cesarean section at term for obstetric reasons.
Endothelin concentration was found to be higher in the umbilical vein
and artery blood of women of African origin. Higher production of end
othelins in the fetoplacental unit may place these women at a greater
risk of preeclampsia.