In contrast to the reliable imaging of the adrenal gland in infants an
d children, transabdominal sonography of the adrenal glands is often u
nsuccessful. Aim: To improve the imaging of the adrenal glands with hi
gh resolution in order to obtain information on even small changes in
these organs. Method: Adrenal glands taken from human cadavers were in
vestigated using a 7.5 MHz transducer. Thereafter, endosonographic ima
ging was investigated in 5 human cadavers using an endosonoscope PENTA
X FG32 UA (longitudinal sector scanning, 7.5 MHz). Furthermore, the ad
renal glands were imaged in a total of 30 patients with different indi
cations for endosonography. Results: The adrenal glands in 5 human cad
avers could be identified in each case. This was proved in one human c
adaver by endosonographically guided fine needle puncture with consecu
tive preparation of the tissue damage caused by the needle. In a total
of 30 patients with 56 adrenal glands (in 4 cases preview history of
unilateral adrenalectomy), 55 adrenal glands were correctly identified
and evaluated. The only exception was the left adrenal gland of a pat
ient with Billroth-II-stomach, which was slightly pulled to the right
and very small. Healthy adrenal glands are slightly hyperechoic as com
pared to the parenchyma of the kidney and have echogeneity comparable
to other endocrinal organs such as the testicles or the thyroid. Endos
onographic imaging of the adrenal glands is far superior in resolution
and determination to transabdominal sonography. In 18 of 30 patients
(60%) endosonography provided additional diagnostic information compar
ed to conventional sonography. Conclusion: Endosonography of the adren
al glands enables imaging of these organs with high resolution using a
7.5 MHz transducer from a distance of 1-2 cm.