GASTRIC AND DUODENAL-ULCERS DURING PREGNANCY

Citation
Ms. Cappell et A. Garcia, GASTRIC AND DUODENAL-ULCERS DURING PREGNANCY, Gastroenterology clinics of North America, 27(1), 1998, pp. 169
Citations number
170
Categorie Soggetti
Gastroenterology & Hepatology
ISSN journal
08898553
Volume
27
Issue
1
Year of publication
1998
Database
ISI
SICI code
0889-8553(1998)27:1<169:GADDP>2.0.ZU;2-M
Abstract
The frequency, symptoms, and complication rate of peptic ulcer disease appear to decrease during pregnancy significantly. Clinicians, howeve r, often have to treat dyspepsia or pyrosis of undetermined cause beca use the frequency of pyrosis increases during pregnancy. Physicians ar e reluctant to perform esophagogastroduodenoscopy (EGD) during pregnan cy for pyrosis to reliably differentiate gastroesophageal reflux from peptic ulcer disease. Dyspepsia or pyrosis during pregnancy first shou ld be treated with dietary and lifestyle changes, together with antaci ds or sucralfate. When symptoms persist, H-2 receptor-antagonists are recommended. If symptoms continue and are severe despite these interve ntions, the patient should be evaluated for possible EGD or proton pum p inhibitor therapy during the second or third trimester.