TRITERPENOID SAPONINS FROM SPERGULARIA-RAMOSA

Six new oleanene glycosides were isolated from the MeOH extract of the aerial parts of Spergularia ramosa. They possess gypsogenin or quilla ic acid as the aglycons. The disaccharide moiety linked to C-3 of the aglycons is made up of galactose (or glucose) and glucuronic acid (or glucose); the pentasaccharide moiety linked to C-28 is made up of gluc ose (or galactose), xylose, rhamnose, fucose, and arabinose. Their str uctures were elucidated by 1D and 2D NMR experiments including H-1-H-1 (DQF-COSY, 1D TOCSY, 2D HOHAHA, ROESY) and H-1-C-13 (HSQC, HMBC) spec troscopy.