NEW IMIDAZOLE ALKALOIDS AND ZINC-COMPLEXES FROM THE MICRONESIAN SPONGE LEUCETTA CF. CHAGOSENSIS

Authors
FU X SCHMITZ FJ TANNER RS KELLYBORGES M
Citation
X. Fu et al., NEW IMIDAZOLE ALKALOIDS AND ZINC-COMPLEXES FROM THE MICRONESIAN SPONGE LEUCETTA CF. CHAGOSENSIS, Journal of natural products, 61(3), 1998, pp. 384-386
Citations number
20
Categorie Soggetti
Chemistry Medicinal","Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
61
Issue
3
Year of publication
1998
Pages
384 - 386
Database
ISI
SICI code
0163-3864(1998)61:3<384:NIAAZF>2.0.ZU;2-U
Abstract
Four new imidazole alkaloids, 2-5, along with the known isonaamidine B (1) were isolated from a Pacific sponge, Leucetta cf. chagosensis, co llected from Yap, Federated States of Micronesia. Among these, 4 and 5 are zinc complexes derived from isonaamidine B and isonaamidine D. Th e structures of the new compounds were elucidated from spectral data. Isonaamidine D (3) showed weakly antifungal activity against Aspergill us niger with MIC = 100 mu g/mL.