In this article, we prove a conjecture of Borel, which states that the
inclusion of the space of automorphic forms into the space of all C-i
nfinity-functions induces an isomorphism on the cohomology with coeffi
cients in a finite-dimensional representation. We also prove that ever
y automorphic form is a sum of derivatives of Eisenstein series and ap
ply these results to the generalisation of the Manin-Drinfeld theorem
and to the trace formula for Hecke operators.