E. Chabas et al., POSTOPERATIVE RESPIRATORY-FUNCTION IN CHILDREN AFTER ABDOMINAL-SURGERY - A COMPARISON OF EPIDURAL AND INTRAMUSCULAR MORPHINE ANALGESIA, Anaesthesia, 53(4), 1998, pp. 393-397
Thirty children undergoing urological and abdominal surgery were enter
ed into a randomised trial comparing the effects of epidural and intra
muscular morphine on postoperative respiratory function. The forced vi
tal capacity and the forced expired volume in is were measured before
and 6 h after surgery and on each of the following seven days. Signifi
cant decreases (p < 0.01) in forced vital capacity and forced expired
volume in is were seen after surgery. After the first postoperative da
y, a gradual recovery in pulmonary function was observed but the measu
red parameters had not returned to their pre-operative control values
by the end of the study. There were no statistically significant diffe
rences between the two groups during the study with respect to forced
vital capacity and forced expired volume in 1 s. The quality of analge
sia was better in the epidural morphine group than in the intramuscula
r morphine group. The incomplete recovery of pulmonary function sugges
ts that pain is not the only cause of postoperative respiratory change
s in these patients.