CONTROL OF VSG GENE-EXPRESSION SITES IN TRYPANOSOMA-BRUCEI

Authors
BORST P BITTER W BLUNDELL PA CHAVES I CROSS M GERRITS H VANLEEUWEN F MCCULLOCH R TAYLOR M RUDENKO G
Citation
P. Borst et al., CONTROL OF VSG GENE-EXPRESSION SITES IN TRYPANOSOMA-BRUCEI, Molecular and biochemical parasitology, 91(1), 1998, pp. 67-76
Citations number
57
Categorie Soggetti
Parasitiology
Journal title
Molecular and biochemical parasitology → ACNP
ISSN journal
01666851
Volume
91
Issue
1
Year of publication
1998
Pages
67 - 76
Database
ISI
SICI code
0166-6851(1998)91:1<67:COVGSI>2.0.ZU;2-1
Abstract
Antigenic variation in African trypanosomes continues to be one of the most elaborate and intriguing strategies ever devised by a protozoan parasite to avoid complete destruction by the immune defense of its ma mmalian host. Here we review some of the recent advances in our unders tanding of this strategy, concentrating on (unpublished) work from our laboratory. (C) 1998 Francqui Foundation. Published by Elsevier Scien ce B.V. All rights reserved.