A METABOLIC MODEL DESCRIBING GROWTH AND SUBSTRATE UPTAKE OF TRIGONOPSIS-VARIABILIS

Citation
Fj. Montes et al., A METABOLIC MODEL DESCRIBING GROWTH AND SUBSTRATE UPTAKE OF TRIGONOPSIS-VARIABILIS, Enzyme and microbial technology, 22(5), 1998, pp. 329-334
Citations number
11
Categorie Soggetti
Biothechnology & Applied Migrobiology
ISSN journal
01410229
Volume
22
Issue
5
Year of publication
1998
Pages
329 - 334
Database
ISI
SICI code
0141-0229(1998)22:5<329:AMMDGA>2.0.ZU;2-M
Abstract
As a part of the study on the production of the enzyme D-Amino acid ox idase (D-AAO) by the yeast Trigonopsis variabilis, a chemically struct ured model capable of explaining cellular growth and substrate uptake of T. variabilis is presented. The model makes use of a simple sequenc e of biochemical reactions produced inside the cell and is capable of simulating a range of metabolic responses obtained front the T. variab ilis growth in discontinuous culture. The model can serve to understan d the behavior of the yeast under different growth conditions and coul d be used as a basis for rile design of an industrial fermentor for D- AAO production. Since some modifications have been introduced to the b asic metabolic model to provide even more generality, this new model c an be applied to any yeast growing under discontinuous conditions. (C) 1998 Elsevier Science Inc.