In the simplified Couinaud classification, in which the liver is divid
ed into eight segments, each supplied by a central vasculo-biliary she
ath, little attention is given to the high prevalence of anatomical va
riations which occur, especially in the right hemiliver. Using volumet
ric acquisition techniques, such as magnetic resonance imaging or spir
al computed tomography scanning, detailed insight into the individual
segmental anatomy can now be obtained in a non-invasive manner. The si
gnificance of this anatomical insight lies in the planning of anatomic
al resections, whereby the relationship between tumour and individual
segmental anatomy can be depicted in a three-dimensional format. As su
ch, three dimensional (3D) liver imaging helps to design an individual
ised resection, tailored to the topographical relationship between ind
ividual segmental anatomy and tumour tissue present. Three dimensional
liver imaging is of most practical value if a resection of one or mor
e segments or sectors is considered, especially in the right hemiliver
. In these cases, 3D liver imaging can demonstrate the precise locatio
n of the scissuras to the surgeon pre-operatively.