A FACILE ALDOL-ISOMERIZATION ROUTE TO 3-ALKYLDIHYDROPYRIDINONE WITH ACHIRAL AZOCINE RING

Authors
TORISAWA Y SOE T KATOH C MOTOHASHI Y NISHIDA A HINO T NAKAGAWA M
Citation
Y. Torisawa et al., A FACILE ALDOL-ISOMERIZATION ROUTE TO 3-ALKYLDIHYDROPYRIDINONE WITH ACHIRAL AZOCINE RING, Heterocycles, 47(2), 1998, pp. 655-659
Citations number
46
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
47
Issue
2
Year of publication
1998
Pages
655 - 659
Database
ISI
SICI code
0385-5414(1998)47:2<655:AFART3>2.0.ZU;2-B
Abstract
An efficient protocol was devised for the synthesis of the chiral dihy dropyridinone derivative (19), which involves an aldol-type coupling r eaction between N-alkylpiperidin-2-one and Garner aldehyde followed by a silane-Rh-mediated olefin isomerization.