Kj. Stewart et al., MANDIBULAR DISTRACTION OSTEOGENESIS - A COMPARISON OF DISTRACTION RATES IN THE RABBIT MODEL, Journal of cranio-maxillo-facial surgery, 26(1), 1998, pp. 43-49
The rabbit model has been used to study the effects of different rates
of distraction upon mandibular bone, Bilateral distraction was perfor
med at two different rates anterior to the molar teeth, Both experimen
tal groups were significantly inferior to sham operated controls in te
rms of bone density (DEXA) and mechanical testing. No difference in ne
w bone formation between the two distraction rates was detected by the
se modalities, However, histological examination revealed non-union to
be more common in the rapidly distracted group, This suggests that at
tempts to shorten the duration of external fixation in clinical mandib
ular distraction osteogenesis should be by methods other than more rap
id distraction.