IMMUNOSUPPRESSIVE THERAPY OF CHRONIC MYOCARDITIS IN CHILDREN - 3 CASES AND THE DESIGN OF A RANDOMIZED PROSPECTIVE TRIAL OF THERAPY

Authors
SCHMALTZ AA DEMEL KP KALLENBERG R NEUDORF U KANDOLF R KLINGEL K BULTMANN B
Citation
Aa. Schmaltz et al., IMMUNOSUPPRESSIVE THERAPY OF CHRONIC MYOCARDITIS IN CHILDREN - 3 CASES AND THE DESIGN OF A RANDOMIZED PROSPECTIVE TRIAL OF THERAPY, Pediatric cardiology, 19(3), 1998, pp. 235-239
Citations number
21
Categorie Soggetti
Cardiac & Cardiovascular System",Pediatrics
Journal title
Pediatric cardiology → ACNP
ISSN journal
01720643
Volume
19
Issue
3
Year of publication
1998
Pages
235 - 239
Database
ISI
SICI code
0172-0643(1998)19:3<235:ITOCMI>2.0.ZU;2-S
Abstract
Three infants, each with a clinical picture of dilated cardiomyopathy, underwent endomyocardial biopsy. Immunohistologic analysis revealed c hronic myocarditis. In one infant, a postviral etiology of chronic myo carditis could be assessed on the basis of molecular techniques. Thera py with azathioprine and prednisone resulted in the normalization of e chocardiographic findings. Based on these observations, a randomized, multicenter treatment study of chronic myocarditis in children (TCMC) has been initiated.