HOLOPROSENCEPHALY MANIFESTING WITH FUSION OF THE GYRI CINGULI

In this paper we report a 7-month-old boy with lobar holoprosencephaly in whom midline interhemispheric fusion occured between thickened gyr i cinguli of both hemispheres at the middle frontal region, This anoma ly appears to be a variation of a recently recognized type of holopros encephaly associated with midline interhemispheric fusion and atypical callosal dysgenesis. in contrast to the previously reported a few cas es, in our patient the corpus callosum was thinned but intact. III add ition, the condition was associated with diffuse cortical dysplasia. T he malformations in this patient is of interest because it contributes to our understanding of variations of holoprosencephaly.