USE OF A NEW DIAMINOBUTANE DENDRIMER IN ELECTROKINETIC CAPILLARY CHROMATOGRAPHY

A modified polyamidoamine-starburst dendrimer (PAMAM-SBD), 16-cascade: (1,4-diaminobutane)[4-1,4] :(1,6-diaza-7-oxo-nonylidene)(2):propanoic acid methyl ester (DABD), was synthesized and used as a carrier in ele ctrokinetic capillary chromatography. The utility of DABD is demonstra ted with the separation of a mixture of naphthalene derivatives and fi ve neutral aromatic molecules without the need for an organic solvent as a modifier. Separation of a mixture of five neutral aromatic molecu les were optimized through dendrimer concentration, pH, and organic mo difier. The modified polyamidoamine-starburst dendrimer offered select ivity for polynuclear aromatic hydrocarbons as well as naphthalene bas ed derivatives. However, DABD did not provide as much selectivity for neutral aromatic compounds in the presence of organic modifier.