P. Sonnenberg et al., THE EFFECT OF DOSAGE CARDS ON COMPLIANCE WITH DIRECTLY OBSERVED TUBERCULOSIS THERAPY IN-HOSPITAL, The international journal of tuberculosis and lung disease, 2(2), 1998, pp. 168-171
We evaluated the effect of a dosage card signed by both patient and he
alth worker on compliance in a tuberculosis ward. Compliance was asses
sed by testing a urine specimen from each patient for the presence of
isoniazid and rifampicin pre-intervention and at two weeks, six weeks
and 16 months post-intervention, Pre-intervention compliance was 62% a
nd increased to 88%, 91% and 93% in the short, medium and long-term, r
espectively (P = 0.03, P = 0.02, P < 0.01). The assumption that direct
ly observed therapy is successfully practised in hospital is not alway
s correct. Simple inexpensive measures can improve compliance and have
an impact on tuberculosis control.