PREPARATION OF VESICLES FROM HYDROTROPE SOLUTIONS

Vesicles were prepared by dilution with water of hydrotrope (sodium xy lene sulfonate) solutions for a nonionic surfactant Laureth 4 (Brij(R) 30). The results showed the sodium xylene sulfonate (SXS) to solubili ze the nonionic surfactant to a high degree, 40% by weight, into an is otropic solution. The vesicle dispersions prepared by dilution contain ed 3.2% by weight of the nonionic surfactant in equilibrium with an aq ueous continuous phase of only 0.4% SXS and 0.04% Laureth 4. Their sta bility was superior to vesicles formed by dispersing the lamellar liqu id crystal directly.