MULTIPLE LOWER-LIMB NON-OSSIFYING FIBROMAS IN SIBLINGS WITH NEUROFIBROMATOSIS

Non-ossifying fibromas are common benign lesions of tubular long bones . There is recognized association of these bony lesions with neurofibr omatosis type 1 although the presence of non-ossifying fibromas in fam ilial members with the condition has not previously been reported. We report two siblings with neurofibromatosis and radiological evidence o f multiple lower limb non-ossifying fibromas. Both patients presented with pain in the knees and a pathological fracture was observed in one case. Patients with multiple non-ossifying fibromas should be examine d carefully for other evidence of neurofibromatosis. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.