BRONCHIAL TEMPERATURE REFLECTS TRANSCAPILLARY HEAT-TRANSPORT OF ISOLATED BLOOD-PERFUSED RABBIT LUNGS

The pulmonary capillaries are in such close proximity to the terminal airways that changes in capillary blood temperature should also cause changes in bronchial wall temperature. Therefore, we hypothesized that injection of cold solutions into the pulmonary artery would yield bro nchial temperature-time curves similar to those in the pulmonary arter y and left atrium. These bronchial curves should mainly represent the capillary bed. Isolated rabbit lungs (n=8) were ventilated (5% CO2 in air) and perfused (autologous blood, 37 degrees C) at various flow rat es (50-200 mL.min(-1)). Thermistor probes (diameter 0.46 mm) registere d temperature changes in the pulmonary artery, at the bronchial wall ( wedge position) and in the left atrium after injection of 0.8 mL Ringe r's lactate (0 degrees C) into the pulmonary artery. Bronchial tempera ture-time curves were found to resemble ''dilution'' curves located be tween pulmonary arterial and left atrial curves, Independent of flow r ate, their appearance times, peaks and calculated mean transit times w ere between those from the pulmonary artery and the left atrium. We co nclude that bronchial temperature-time curves reflect transcapillary h eat transport and that this approach might be useful in gaining furthe r information about vascular transport processes in the interior of th e lung.