DESYMMETRISATION OF DIENYLSILANES - STEREOSELECTIVE ACCESS TO CYCLITOLS AND CARBA-SUGARS

Authors
LANDAIS Y
Citation
Y. Landais, DESYMMETRISATION OF DIENYLSILANES - STEREOSELECTIVE ACCESS TO CYCLITOLS AND CARBA-SUGARS, Chimia, 52(3), 1998, pp. 104-111
Citations number
70
Categorie Soggetti
Chemistry
Journal title
Chimia → ACNP
ISSN journal
00094293
Volume
52
Issue
3
Year of publication
1998
Pages
104 - 111
Database
ISI
SICI code
0009-4293(1998)52:3<104:DOD-SA>2.0.ZU;2-E
Abstract
The diastereo-and enantioselective functionalisation of 1,4-cyclohexad ienylsilanes using Sharpless asymmetric dihydroxylation and aminohydro xylation offers a straightforward access to various classes of potent inhibitors of glycosidases. The scope and limitation of this desymmetr isation method is illustrated here with the synthesis of various condu ritols, carba-sugars and carba-C-disaccharides.