THE FIRST SYNTHESIS OF CONIOCHAETONE-A AND CONIOCHAETONE-(+ -)-B - 2 BENZOPYRANONE DERIVATIVES/

Authors
MORI K AUDRAN G MONTI H
Citation
K. Mori et al., THE FIRST SYNTHESIS OF CONIOCHAETONE-A AND CONIOCHAETONE-(+ -)-B - 2 BENZOPYRANONE DERIVATIVES/, Synlett, (3), 1998, pp. 259-260
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
3
Year of publication
1998
Pages
259 - 260
Database
ISI
SICI code
0936-5214(1998):3<259:TFSOCA>2.0.ZU;2-K
Abstract
An efficient synthesis of coniochaetone A and of racemate coniochaeton e B was achieved by a short five-step procedure from methyl di-O-methy l-p-orsellinate. The key step is a cascade reaction of -methoxy-4'-met hyl-2-(methylsulfinyl)-acetophenone with succindialdehyde in the prese nce of piperidine which allows the direct building of the tricyclic be nzopyranone structure.