IN-VITRO ACTIVITY OF A NEW 8-METHOXYQUINOLONE, BAY-12-8039, AGAINST CHLAMYDIA-PNEUMONIAE

Authors
ROBLIN PM HAMMERSCHLAG MR
Citation
Pm. Roblin et Mr. Hammerschlag, IN-VITRO ACTIVITY OF A NEW 8-METHOXYQUINOLONE, BAY-12-8039, AGAINST CHLAMYDIA-PNEUMONIAE, Antimicrobial agents and chemotherapy, 42(4), 1998, pp. 951-952
Citations number
17
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
42
Issue
4
Year of publication
1998
Pages
951 - 952
Database
ISI
SICI code
0066-4804(1998)42:4<951:IAOAN8>2.0.ZU;2-N
Abstract
The in vitro susceptibilities of 10 strains of Chlamydia pneumoniae to a new 8-methoxyquinolone, BAY 12-8039, and to ofloxacin, doxycycline, and erythromycin were determined. The activity of BAY 12-8039 was sim ilar to that of ofloxacin, with a MIC at which 90% of the isolates had no inclusions and a minimal chlamydicidal concentration at which 90% of the isolates had no inclusions after passage of 1.0 mu g/ml, but th is activity was less than those of doxycycline and erythromycin.