PATIENT-EVALUATION AND COMPARISON OF THE RECOVERY PROFILE BETWEEN PROPOFOL AND THIOPENTONE AS INDUCTION-AGENTS IN DAY SURGERY

The patient's subjective perception of the quality of his/her recovery after day case anaesthesia with propofol or thiopentone as induction agents is still controversial. The authors investigated the perception and quality of awakening after anaesthesia during the recovery period and at 24 hours and 72 hours, in outpatients undergoing anaesthesia i nduced either with propofol or thiopentone and maintained with a volat ile anaesthetic. In a double-blind study in adults undergoing knee art hroscopy in a day surgery unit, propofol and thiopentone were compared as induction agents in 60 randomized outpatients. A critical Flicker Fusion Threshold test (CFFT), verbal test for anxiety, visual analog s cale for anxiety and pain, and questionnaires were used to assess obje ctively and subjectively the quality of anaesthesia and awakening duri ng the postoperative period. Demographic data and mean duration of ana esthesia were similar. In the propofol group, patients awake more rapi dly (9.2+/-5.8 vs 12.3+/-5.8 min) (P<0.05); however, the CFFT measurem ents did not show any significant difference between the groups, excep t at time=0 min, when 17 patients in the propofol group were able to p erform the test versus only 10 patients in the thiopentone group (P<0. 05). At 4, 24, and 72 hours postoperatively, the authors were unable t o detect any difference between the two groups. Except for early recov ery, there were no differences between the intermediate and late recov ery profiles, when propofol or thiopentone was used as the anaesthetic induction agent in day surgery.