S. Segal et al., THROMBOCYTOPENIA WITH THE HELLP-SYNDROME - REPORT OF 2 CASES WITH REVERSAL IN NORMOTENSIVE AND NONPROTEINURIC GRAVIDAS, Journal of reproductive medicine, 43(3), 1998, pp. 227-229
BACKGROUND: In the absence of hypertension and liver enzymes and low p
latelet count (HELLP syndrome) present a diagnostic and therapeutic pr
oblem. CASES: Two atypical cases occurred of HELLP syndrome diagnosed
by hemolysis, elevated liver enzymes and low platelet count. The patie
nts presented early in the third trimester with epigastric pain and la
cked the usual signs of preeclampsia, such as hypertension and protein
uria. The patients were managed expectantly; during this time they bec
ame hypertensive, but the thrombocytopenia resolved. CONCLUSION: Pregn
ant women with hemolysis, elevated liver enzymes and thrombocytopenia
who do not have hypertension or proteinuria should undergo complete di
agnostic evaluation. If other etiologies are ruled out, the patient sh
ould be managed as appropriate for severe preeclampsia complicated by
the HELLP syndrome.