Background: The prevalence of radiographically defined vertebral defor
mities, as a marker of vertebral osteoporosis, was calculated in a pop
ulation based cross-sectional survey in Germany. Method: Lateral spine
X-rays were taken according to a standardized protocol and evaluated
centrally. Three thousand nine hundred and eighty subjects (2064 male
and 1916 female) aged 50 to 79 years, have been examined in 8 German c
enters. Results: Based on McCloskey's method of deformity definition t
he age-standardized mean prevalence of vertebral deformities in German
y was 10.2% for males and 10.5% for females. Based on the definition b
y Melton/Eastell a significant higher prevalence was calculated (males
17.8%, females 18.7%). The prevalence increased with age in both sexe
s with a steeper increase in females. There was no difference in East
and West German populations. There were substantial variations between
the centers regarding the prevalence of deformities in females and ma
les.