FIRST ESTABLISHED PREGNANCY AFTER CONTROLLED OVARIAN HYPERSTIMULATIONWITH RECOMBINANT FOLLICLE-STIMULATING-HORMONE AND THE GONADOTROPIN-RELEASING-HORMONE ANTAGONIST GANIRELIX (ORG-37462)

This case report describes the first established pregnancy after the u se of gonadotrophin-releasing hormone (GnRH) antagonist, ganirelix (Or g 37462; Organon), to prevent a premature luteinizing hormone surge du ring ovarian hyperstimulation with recombinant human follicle stimulat ing hormone (rhFSH), The pregnancy progressed normally and ended with the birth of a healthy boy and a girl after an elective Caesarean sect ion at gestational age of 37 weeks. This case illustrates, for the fir st time, the use of a GnRH antagonist in combination with a pure FSH p reparation for ovarian stimulation.