Bm. Eley et Sw. Cox, ADVANCES IN PERIODONTAL DIAGNOSIS 5 - POTENTIAL INFLAMMATORY AND IMMUNE MARKERS, British Dental Journal, 184(5), 1998, pp. 220-223
The potential inflammatory and immune markers that might detect period
ontal disease severity or activity are examined. The role of inflammat
ory and immune factors passing from the tissues into the gingival crev
icular fluid (GCF) are considered. GCF sampling is a necessary part of
all diagnostic tests based on gingival and periodontal tissue factors
. Inflammatory and immune factors found in GCF are reviewed with speci
al reference to the humoral immune response, complement, cytokines and
prostaglandins. The possible development of diagnostic tests based on
these factors are discussed.