In. Sills et R. Rapaport, NON-INSULIN-DEPENDENT DIABETES-MELLITUS IN A PREPUBERTAL CHILD WITH PRADER-WILLI-SYNDROME, Journal of pediatric endocrinology & metabolism, 11(2), 1998, pp. 281-282
Diabetes mellitus has only rarely been reported in prepubertal childre
n with Prader-Willi syndrome, All reported children have required insu
lin therapy. We report the development of a previously unrecognized as
sociation of non-insulin dependent diabetes mellitus in an obese 6 yea
r-old child with Prader-Willi syndrome. She has never developed ketosi
s or acidosis, and she has been treated with oral hypoglycemic medicat
ion.