The cognitive models of panic disorder with (PDA) or without (PD) agor
aphobia are now widely recognised. These models propose that patients
misinterpret external or internal cues in a catastrophic manner and as
a result of these catastrophic cognitions the symptoms are maintained
There is now a large body of empirical evidence for this proposal and
the aim of this paper is to systematically review the literature to e
valuate whether the empirical evidence supports the contribution of ca
tastrophic cognitions to PD and PDA. Empirical studies using different
methodologies, such as interview, questionnaire, self-monitoring anal
in vivo techniques are reviewed. The results indicate there is substa
ntial empirical evidence in support of the central role of catastrophi
c cognition in cognitive models. Different methodologies provided conv
ergent support for the importance of catastrophic cognitions in the ma
intenance of panic disorder and agoraphobia. Limitations in the interp
retation of the existing research are highlighted and future research
directions are proposed. (C) 1998 Elsevier Science Ltd.