LANGERHANS CELL HISTIOCYTOSIS OF THE SKIN

Cutaneous involvement in Langerhans cell histiocytosis (LCH) occurs in 50% of cases and may be the presenting feature. It is, therefore, imp ortant to recognize the wide spectrum of clinical disease that this di sorder may adopt in the skin. Cutaneous involvement is not necessarily a benign feature and many patients progress to multi-system disease. There are a number of treatments available for cutaneous LCH. The rati onale is to start with the simplest treatment and progress to systemic or interventional therapy as needed.