This article presents a brief overview of the physiology of homeostasi
s in the horse and discusses the units of measurement by which dissolv
ed electrolytes are assessed. Differences in electrolyte composition b
etween compartments of the body and the manner in which water is excha
nged between them are reviewed. The mechanisms by which alterations in
osmolality and effective circulating volume are detected and the phys
iological responses to those alterations are presented.