SOLID-PHASE SYNTHESIS OF OLIGONUCLEOTIDE PHOSPHOROTHIOATE ANALOGS USING BIS(ETHOXYTHIOCARBONYL)TETRASULFIDE AS A NEW SULFUR-TRANSFER REAGENT

Authors
ZHANG ZD NICHOLS A ALSBETI M TANG JX TANG JY
Citation
Zd. Zhang et al., SOLID-PHASE SYNTHESIS OF OLIGONUCLEOTIDE PHOSPHOROTHIOATE ANALOGS USING BIS(ETHOXYTHIOCARBONYL)TETRASULFIDE AS A NEW SULFUR-TRANSFER REAGENT, Tetrahedron letters, 39(17), 1998, pp. 2467-2470
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
17
Year of publication
1998
Pages
2467 - 2470
Database
ISI
SICI code
0040-4039(1998)39:17<2467:SSOOPA>2.0.ZU;2-0
Abstract
A new sulfur-transfer reagent, bis(ethoxythiocarbonyl)tetrasulfide (1) , has been prepared and used for the synthesis of oligonucleotide phos phorothioates via solid phase phosphoramidite approach. (C) 1998 Elsev ier Science Ltd. All rights reserved.