NEW AND EFFICIENT SYNTHETIC ROUTES TO 1-DEOXY-D-XYLULOSE

Authors
GINER JL
Citation
Jl. Giner, NEW AND EFFICIENT SYNTHETIC ROUTES TO 1-DEOXY-D-XYLULOSE, Tetrahedron letters, 39(17), 1998, pp. 2479-2482
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
17
Year of publication
1998
Pages
2479 - 2482
Database
ISI
SICI code
0040-4039(1998)39:17<2479:NAESRT>2.0.ZU;2-U
Abstract
The biochemically important deoxysugar 1-deoxy-D-xylulose was synthesi zed by improved methods. D-Tartaric acid is the starting material for a synthesis which proceeds via the intermediacy of 2,3,4-tribenzyl-D-t hreitol. Another, highly efficient route used the Sharpless asymmetric dihydroxylation of 5-benzyloxy-3-penten-2-one as its key step. These syntheses are especially useful for isotopic labeling. (C) 1998 Publis hed by Elsevier Science Ltd. All rights reserved.