The purpose of our study was the assessment of the diagnostic value of
vacuum core biopsy, which promises high accuracy by minimally invasiv
e percutaneous excision of 1-2 cm(3) of tissue. The materials used wer
e a digital stereotaxic biopsy table (Fischer Imaging) and a Mammotome
-gun (Biopsys). A total of 236 patients with 261 predominantly indeter
minate lesions (indeterminate: 230; suspicious: 26; malignant: 5) unde
rwent vacuum core biopsy (VCB). Verification was as follows: (a) demon
stration of complete or partial removal of the lesion or replacement o
f the lesion by a small hematoma by comparison the pre-and post-VCB ma
mmogram; (b) reexcision of 45 malignant and 6 borderline lesions; (c)
radiologic-histologic correlation; and (d) 6-month-follow-up mammogram
s in 129 cases. Two VCBs were not possible because very fine microcalc
ifications could not be visualized. Two puncture errors occurred which
, however, were immediately recognized and VCB was repeated. Based on
the above verification a 100 % accuracy was achieved. No relevant side
effects occurred. Except for 2 cases mammographically hardly any scar
ring was visible. Based on the excellent accuracy and excellent tolera
nce of the procedure VCB appears to be the future method of choice for
the workup of those indeterminate mammographically detected lesions t
hat up to now have still required surgical biopsy.