The aim of our study was to compare gradient-spin-echo (GRASE) to fast
-spin-echo (FSE) sequences for fast T2-weighted MR imaging of the brai
n. Thirty-one patients with high-signal-intensity lesions on T2-weight
ed images were examined on a 1.5-T MR system. The FSE and GRASE sequen
ces with identical sequence parameters were obtained and compared side
by side. Image assessment criteria included lesion conspicuity, contr
ast between different types of normal tissue, and image artifacts. In
addition, signal-to-noise, contrast-to-noise, and contrast I ratios an
d were determined. The FSE technique demonstrated more lesions than GR
ASE and with generally better conspicuity. Smaller lesions in particul
ar were better demonstrated on FSE because of lower noise and slightly
weaker image artifacts. Gray-white differentiation was better on FSE.
Ferritin and hemosiderin depositions appeared darker on GRASE, which
resulted in better contrast. Fatty tissue was less bright on GRASE. Wi
th current standard hardware equipment, the FSE technique seems prefer
able to GRASE for fast T2-weighted routine MR imaging of the brain. Fo
r the assessment of hemosiderin or ferritin depositions, GRASE might b
e considered.