CONTEMPORANEOUS ACUTE MYELOID-LEUKEMIA AND SARCOIDOSIS - REPORT OF 3 CASES

Authors
PAGANO L VISANI G FERRARA F CENACCHI A BONINI A EQUITANI F FUSO L PISCITELLI R PAGLIARI G
Citation
L. Pagano et al., CONTEMPORANEOUS ACUTE MYELOID-LEUKEMIA AND SARCOIDOSIS - REPORT OF 3 CASES, Sarcoidosis vasculitis and diffuse lung diseases, 15(1), 1998, pp. 67-70
Citations number
23
Categorie Soggetti
Respiratory System
Journal title
Sarcoidosis vasculitis and diffuse lung diseases → ACNP
ISSN journal
11240490
Volume
15
Issue
1
Year of publication
1998
Pages
67 - 70
Database
ISI
SICI code
1124-0490(1998)15:1<67:CAMAS->2.0.ZU;2-3
Abstract
Three cases of contemporaneous acute myeloid leukaemia (AML) and sarco idosis are described. The possible pathogenic mechanisms concerning th eir concurrent appearance are discussed: if sarcoidosis impaired T-cel l response, it could perhaps predispose the development of AML; altern atively, the development of sarcoidosis during AML may be due to a rea ction linked to a diffuse release of tumour antigens with a subsequent formation of a non-caseating granulomata.