Background: The authors examined recent changes in the number and prop
ortion of patients prescribed antidepressants by psychiatrists in outp
atient private practice and characterized antidepressant prescription
patterns by patient age, sex, race, payment source, and clinical diagn
osis. Methods: The authors analyzed physician-reported data from the 1
985 and 1993-1994 National Ambulatory Medical Care Survey, focusing on
visits to physicians specializing in psychiatry. Logistic regressions
were used to examine associations between survey year and antidepress
ant prescription, adjusting for the presence of other variables. Resul
ts: The proportion of outpatient psychiatric visits in which an antide
pressant was prescribed increased from 23.1% (95% confidence interval
[CI], 19.7%-26.5%) in 1985 to 48.6% (95% CI, 47.5%-49.7%) in 1993-1994
. After controlling for several patient variables, psychiatric patient
s were approximately 2.3 (95% CI, 1.8-2.9) times more likely to receiv
e an antidepressant in 1993-1994 than in 1985. In 1993-1994, selective
serotonin reuptake inhibitors accounted for approximately half of the
psychiatric visits with an antidepressant prescription. Increases in
the rate of antidepressant prescription were particularly evident for
children and young adults; whites; new patients; and patients with adj
ustment disorders, personality disorder, depression not otherwise spec
ified or dysthymia, and some anxiety disorders. Conclusions: During th
e late 1980s and early 1990s, there was a significant increase in the
prescription of antidepressants by office-based psychiatrists. This in
crease was greatest for patients with less severe psychiatric disorder
s.