A CASE OF GUILLAIN-BARRE-SYNDROME DEVELOPED MINIMAL CHANGE NEPHROTIC SYNDROME SIMULTANEOUSLY

A case who developed Guillain-Barre syndrome (GBS) and nephrotic syndr ome (NS) simultaneously is reported, In this case, the onset of nephro tic change of proteinuria coincided with the development of the neurol ogical disturbance, Analysis of renal biopsy by light, immunofluoresce nt and electron microscopy showed minor glomerular abnormalities, The occurrence of GBS in association with NS is rare, and moreover most ca ses in the previous reports had membranous nephropathy, Only 1 case ha d minimal change nephrotic syndrome (MCNS), To our knowledge, this is the first report of a case beneficially treated with glucocorticoids, suggesting that immune disorder may play an important role in the asso ciation between MCNS and GBS.