SYNTHESIS AND ANTIVIRAL ACTIVITY OF NOVEL ISODIDEOXY NUCLEOSIDES WITHEXOCYCLIC METHYLENE

Authors
Citation
Ls. Jeong et Sj. Yoo, SYNTHESIS AND ANTIVIRAL ACTIVITY OF NOVEL ISODIDEOXY NUCLEOSIDES WITHEXOCYCLIC METHYLENE, Bioorganic & medicinal chemistry letters, 8(7), 1998, pp. 847-852
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
ISSN journal
0960894X
Volume
8
Issue
7
Year of publication
1998
Pages
847 - 852
Database
ISI
SICI code
0960-894X(1998)8:7<847:SAAAON>2.0.ZU;2-T
Abstract
Novel isodideoxy nucleosides with exocyclic methylene were synthesized starting from L-xylose utilizing anomeric demethoxylation, Wittig rea ction and Mitsunobu reaction as key steps and evaluated for antiviral activity. (C) 1998 Elsevier Science Ltd. All rights reserved.