SYNTHESIS AND ANTIVIRAL ACTIVITY OF NOVEL ISODIDEOXY NUCLEOSIDES WITHEXOCYCLIC METHYLENE

Authors
JEONG LS YOO SJ
Citation
Ls. Jeong et Sj. Yoo, SYNTHESIS AND ANTIVIRAL ACTIVITY OF NOVEL ISODIDEOXY NUCLEOSIDES WITHEXOCYCLIC METHYLENE, Bioorganic & medicinal chemistry letters, 8(7), 1998, pp. 847-852
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
8
Issue
7
Year of publication
1998
Pages
847 - 852
Database
ISI
SICI code
0960-894X(1998)8:7<847:SAAAON>2.0.ZU;2-T
Abstract
Novel isodideoxy nucleosides with exocyclic methylene were synthesized starting from L-xylose utilizing anomeric demethoxylation, Wittig rea ction and Mitsunobu reaction as key steps and evaluated for antiviral activity. (C) 1998 Elsevier Science Ltd. All rights reserved.