ULCERATIVE POROKERATOSIS

A 54-year-old man presented with multiple annular plaques since infanc y. During the intake of nifedipine and nitroglycerin over a period of 6 years, reddish, eruptive and ulcerative changes were seen in the pre -existing skin lesions on the penis, scrotum and legs. In addition to a typical cornoid lamella, histological examination revealed a band-li ke infiltration beneath the epidermis, liquefaction degeneration of th e basal cell layer and subsequent coagulative necrosis of the keratino cytes. We review similar ulcerative types of porokeratosis in the lite rature and discuss the significance of our unusual case.