UNDERSTANDING THE ELECTROPORATION OF CELLS AND ARTIFICIAL BILAYER-MEMBRANES

Authors
ISAMBERT H
Citation
H. Isambert, UNDERSTANDING THE ELECTROPORATION OF CELLS AND ARTIFICIAL BILAYER-MEMBRANES, Physical review letters, 80(15), 1998, pp. 3404-3407
Citations number
13
Categorie Soggetti
Physics
Journal title
Physical review letters → ACNP
ISSN journal
00319007
Volume
80
Issue
15
Year of publication
1998
Pages
3404 - 3407
Database
ISI
SICI code
0031-9007(1998)80:15<3404:UTEOCA>2.0.ZU;2-U
Abstract
A new physical mechanism is proposed to explain the electroporation of cells based on the electric-field-induced stretching of their curved membrane. The opening of pores simultaneously relaxes the surface tens ion leaving long-lived pores in the membrane. Semiquantitative results are proposed in good agreement with experimental observations on cell s and artificial bilayer membranes.