OVULATION IN HYPERGONADOTROPINAEMIA

A Case Report: Considerable changes of serum FSH, LH and E-2 in respon se to hormonal treatment were recorded in a patient with resistant-ova ry syndrome during one year of observation. The FSH levels ranged init ially from 28 to 180 IU/l; after treatment leuproreline (Lpr) and HMG, respectively, they decreased to 5 to 12 IU/l. Serum E, reacted to inj ections of HMC with a marked increase, but the amplitude of the respon se diminished in subsequent treatment cycles. After one year of observ ation, the patient ovulated spontaneously several times. Conclusion: T he resistant-ovary syndrome is a variant of premature menopause charac terised by a normal supplement of unresponsive follicles which may, ho wever, termporarily regain normal function.