COVALENT IMMOBILIZATION OF OLIGONUCLEOTIDES ON MODIFIED GLASS SILICONSURFACES FOR SOLID-PHASE DNA HYBRIDIZATION AND AMPLIFICATION/

Authors
YANG MS KONG RYC KAZMI N LEUNG AKC
Citation
Ms. Yang et al., COVALENT IMMOBILIZATION OF OLIGONUCLEOTIDES ON MODIFIED GLASS SILICONSURFACES FOR SOLID-PHASE DNA HYBRIDIZATION AND AMPLIFICATION/, Chemistry Letters, (3), 1998, pp. 257-258
Citations number
10
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
3
Year of publication
1998
Pages
257 - 258
Database
ISI
SICI code
0366-7022(1998):3<257:CIOOOM>2.0.ZU;2-X
Abstract
Glass slides and silicon chips were modified with aminosilane and vari ous linker molecules to provide activated surfaces for covalent immobi lization of oligonucleotides under ambient condition, and the surface- attached oligonucleotides remain active for solid-phase DNA hybridizat ion and polymerase chain reaction.