TOTAL SYNTHESIS OF (+)-FURANOMYCIN

Authors
KANG SH LEE SB
Citation
Sh. Kang et Sb. Lee, TOTAL SYNTHESIS OF (+)-FURANOMYCIN, Chemical communications, (7), 1998, pp. 761-762
Citations number
24
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
7
Year of publication
1998
Pages
761 - 762
Database
ISI
SICI code
1359-7345(1998):7<761:TSO(>2.0.ZU;2-D
Abstract
A highly enantioselective total synthesis of (+)-furanomycin 24 has be en achieved via the mercury cation-mediated cyclizations of gamma-hydr oxy alkene 4 and homoallylic trichloroacetimidate 11 to install the tr ans-2,5-disubstituted tetrahydrofuran and the (alpha S)-amino acid sid e chain, respectively.