Diaphragm pacing (DP) by electrical stimulation of the phrenic nerve o
ffers important advantages to a highly select group of patients with r
espiratory paralysis. The patient wears an external radiofrequency (RF
) transmitter over an implanted receiver, and a stimulating current is
induced without the need for any transcutaneous wires. We review the
conditions and requirements of patients who may benefit most from DP.
We outline the preoperative evaluation and procedures for surgical imp
lantation. We discuss the risk of diaphragmatic fatigue posed by initi
ation of DP and the use of gradual conditioning to limit this problem.
Other problems encountered by patients in the course of DP can be min
imized by well-instructed home caregivers and by systematic medical fo
llow-up. Although a few patients derive considerable benefit from DP,
many patients with respiratory paralysis are better treated by less in
vasive means such as nasal bilevel positive airway pressure or intermi
ttent positive pressure ventilation, which we also review.