VITAMIN-E SERUM LEVELS IN RETT-SYNDROME

In order to study the role of vitamin E in the pathogenesis of Rett sy ndrome (RS), we analysed vitamin E serum levels in twenty-eight patien ts affected by this disorder. We found lower vitamin E serum levels in nine cases (32.1%). These results indicated that the oxidative free r adical metabolism may be impaired in a significant percentage of Rett syndrome patients suggesting the need for further studies of tissue vi tamin E in different brain regions. (C) 1998 Elsevier Science B.V.